Postdoctoral Research Associate in Germline Differentiation (Drosophila), Department of Genetics, University of Cambridge

Job Description

The University of Cambridge is hiring a postdoc in germline differentiation in the Department of Genetics. You will study how layers of gene regulation turn a germline stem cell into an egg, using the fruit fly ovary. Pay is £37,694 to £46,049 a year. Applications close on 8 November 2026.

At a glance

• Position: Postdoctoral Research Associate (Fixed Term), reference PC51215
• Group: Dr Felipe Karam Teixeira, Department of Genetics
• Where: Cambridge, United Kingdom
• Pay: £37,694 to £46,049 a year, plus a 2.5% interim pay award
• Duration: 3 years in the first instance; preferred start January or February 2027
• Apply: 8 November 2026

What the Cambridge germline postdoc will work on

• Study the molecular switches that drive germline differentiation in the Drosophila female germline
• Find out how transcription, post-transcriptional control, translation and chromatin work together during oogenesis
• Use methods such as CRISPR-Cas9 editing, tissue-specific RNAi, transgenesis, transcriptomic and epigenomic profiling
• Image cells with immunofluorescence, single-molecule RNA imaging and quantitative confocal microscopy
• Shape the project’s direction, present at international meetings and help write papers

Why this role matters

The group’s recent work mapped how gene expression changes as a stem cell becomes an egg. It found that change comes in ordered waves. This post asks what drives those waves. The answer matters for fertility and for stem cell biology in general.

What the Karam Teixeira group is looking for

• A PhD in molecular biology, genetics, developmental biology, biochemistry, genomics or a related field, or close to finishing one
• A solid research record for your career stage
• The ability to design, run and troubleshoot complex experiments
• Rigorous, quantitative data analysis
• Scientific creativity and independence, and excellent written and spoken communication

Nice to have

• Research in germline, stem cell or developmental biology
• NGS methods such as RNA-seq, ATAC-seq, ChIP-seq, CUT&Tag or Hi-C, and/or confocal microscopy (IF, smFISH or HCR)
• Drosophila genetics helps but is not essential; the group will train you

Pay and location

The further particulars give a salary of £37,694 to £46,049 per annum. The successful candidate also receives a 2.5% interim pay award on top of base salary. Funds are available for three years in the first instance. The job is in Cambridge, UK. The university says all employees must be eligible to live and work in the UK.

How to apply

Apply through the official the Karam Teixeira group page. The closing date is 8 November 2026. Click Apply on the ad page to register with the university’s recruitment system and apply online. Quote reference PC51215. Informal questions go to Dr Felipe Karam-Teixeira (fk319@cam.ac.uk).

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