Senior Scientist, Functional Genomics (In Vivo CRISPR Screening) at Xaira Therapeutics
Job Description
Xaira is hiring a Senior Scientist to lead in vivo CRISPR screening: developing and scaling high-throughput CRISPR screens in mouse models to link genotype to phenotype at scale. The role combines strategic leadership with hands-on work, at the meeting point of mouse models, data science, AI/ML and translational biology.
At a glance
- Team: Functional Genomics
- Location: South San Francisco, California
- Pay: $136,000 – $170,000 a year, as listed
- Apply: open until filled (re-checked 14 October 2026)
What you would do
- Develop, implement and scale high-throughput in vivo CRISPR screening protocols in mouse models
- Drive innovation in experimental workflows and screening methods
- Analyse, interpret and communicate large functional genomics datasets with computational biology and AI/ML teams
- Translate data-driven insights into therapeutic research
Why this role matters
In vivo screens test gene function inside living animals, where the real biology of disease happens, but they are hard to run at scale. Xaira wants to make them large enough to feed its AI models, which makes this a rare role joining cutting-edge genetics with AI-driven drug discovery, with scope to shape how the screening programme grows. It suits scientists with deep in vivo experience.
What Xaira Therapeutics is looking for
- Substantial experience in CRISPR-based functional genomics, including in vivo screening
- Experience with mouse models
- Ability to lead projects while contributing hands-on
Nice to have
- Experience working with machine learning or large-scale data teams
Pay and location
Xaira lists $136,000 to $170,000 a year for this role.
How to apply
Apply through the official Xaira Therapeutics job posting. Xaira Therapeutics’s posting does not give a closing date, so the role is open until filled; ResearchJobs.in will re-check this listing on 14 October 2026. Check the posting for location and work-authorisation details before you apply.
See all our life sciences jobs, or browse more research jobs on ResearchJobs.in.
Hiring institution: Xaira Therapeutics
Official advertisement: job-boards.greenhouse.io
How to prepare for this application
- Screens you ran: describe in vivo CRISPR screens and their scale.
- Mouse models: list the models and readouts you used.
- Data partnership: show work with computational teams.
- Leadership: the role leads a programme.
About Xaira Therapeutics
Xaira is a biotech start-up using AI to discover and develop medicines. It builds generative models to design protein and antibody drugs against hard-to-drug targets, and foundation models of biology and disease for target discovery and patient selection. It is based in the San Francisco Bay Area, Seattle and London.
