Postdoctoral Researcher in Population Pharmacogenetics (African Genomes) at Karolinska Institutet

Job Description

Prof. Volker Lauschke’s research programme at Karolinska Institutet is hiring a postdoctoral researcher in population pharmacogenetics. The project focuses on genetic diversity in African populations and how it affects drug response: finding and characterising variants that matter for efficacy, pharmacokinetics and adverse drug reactions in large genomic and pharmacogenomic datasets, and prioritising some of them for experimental validation.

At a glance

• Position: Postdoctoral researcher (1 post), special fixed-term employment, full time
• Where: Biomedicum, Campus Solna
• PI: Prof. Volker Lauschke, volker.lauschke@ki.se
• Reference: STÖD 2-3619/2026
• Apply by: 26 September 2026
• Apply: 26 September 2026

About the pharmacogenetics postdoc

• Genotype-phenotype analyses and characterisation of pharmacogene haplotypes
• Rare and structural variant analysis, and computational prediction of variant function
• Integrate functional and clinical data
• Prioritise variants for validation with cellular and molecular methods
• Work independently within multidisciplinary international collaborations

What to include in your application

KI asks for documents in English or Swedish: your PhD certificate, a complete CV (with the date and title of your thesis, previous academic positions and distinctions), a complete list of publications, and a summary of your current work of no more than one page. Applications are submitted through KI’s Varbi recruitment system.

What Karolinska Institutet is looking for

• A PhD in pharmacogenetics/pharmacogenomics, human genetics, molecular medicine, bioinformatics, pharmacology or a close field (within three years is an advantage)
• Documented pharmacogenetic or human genetics research, preferably in African or other genetically diverse, under-represented populations
• Experience analysing NGS data: targeted, whole-exome and/or whole-genome sequencing
• Strong computational genetics: variant annotation and prioritisation, association analyses and population-genetic methods
• Pharmacogene-specific analysis of drug-metabolising enzymes, transporters or drug targets, and programming in R or Python

Nice to have

• Rare-variant, haplotype, structural or splice-variant analysis
• Computational prediction of functional consequences of variants

Pay and location

KI sets salaries individually and the advert gives no figure. The post is full time at Campus Solna.

How to apply

Apply through the official Karolinska Institutet page. The closing date is 26 September 2026.

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